Global Biotech Breakthroughs

CARsgen Therapeutics Holdings

Market Cap: HK$9.7b

An investment holding company, engages in discovering, developing, and commercializing chimeric antigen receptor T (CAR-T) cell therapies for the treatment of hematological malignancies, solid tumors, and autoimmune diseases in China.

Sichuan Kelun-Biotech Biopharmaceutical

Market Cap: HK$101.4b

A biopharmaceutical company, engages in the research and development, manufacturing, and commercialization of novel drugs in oncology, immunology, and other therapeutic areas in the People’s Republic of China and internationally.

Ascentage Pharma Group International

Market Cap: HK$24.0b

A clinical-stage biotechnology company, develops therapies for cancers, chronic hepatitis B virus (HBV), and age-related diseases in Mainland China.

Madrigal Pharmaceuticals

Market Cap: US$12.0b

A biopharmaceutical company, focuses on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH) in the United States.

Caris Life Sciences

Market Cap: US$6.7b

An artificial intelligence TechBio company, provides molecular profiling services in the United States and internationally.

Arcutis Biotherapeutics

Market Cap: US$3.1b

A biopharmaceutical company, focuses on developing and commercializing treatments for dermatological diseases.

Cynata Therapeutics

Market Cap: AU$61.7m

Engages in the development and commercialization of proprietary induced pluripotent stem cell and mesenchymal stem cell technology under the Cymerus brand for human therapeutic use in Australia.

Akeso

Market Cap: HK$107.0b

A biopharmaceutical company, engages in the research, development, manufacture, and commercialization of antibody drugs worldwide.

Egetis Therapeutics

Market Cap: SEK 2.3b

A pharmaceutical company, focuses on projects in late-stage development for the treatment of serious diseases with unmet medical needs in the orphan drug segment.

Marker Therapeutics

Market Cap: US$11.9m

A clinical-stage immuno-oncology company, engages in the development and commercialization of novel T cell-based immunotherapies for the treatment of hematological malignancies and solid tumor indications.

3billion

Market Cap: ₩376.9b

Develops technology for rare disease drug discovery using bioinformatics and machine learning technology.

Biovica International

Market Cap: SEK 159.7m

A biotech company, develops and commercializes novel blood-based biomarker assays that enhance the monitoring and predicting of cancer therapies in the European Union, United States of America, and internationally.

Mereo BioPharma Group

Market Cap: US$283.3m

A biopharmaceutical company, develops and commercializes therapeutics for the treatment of oncology and rare diseases in the United Kingdom, the United States, and internationally.

Cutia Therapeutics

Market Cap: HK$2.5b

An investment holding company, engages in the research, development, manufacture, and commercialization of scalp diseases and care products, and skin care products in the People’s Republic of China and Hong Kong.

Suzhou Zelgen Biopharmaceuticals

Market Cap: CN¥26.7b

Suzhou Zelgen Biopharmaceuticals Co., Ltd.

Mesoblast

Market Cap: AU$3.0b

Engages in the development of regenerative medicine products in Australia, the United States, Singapore, and Switzerland.

Legend Biotech

Market Cap: US$5.6b

Through its subsidiaries, operates as a biopharmaceutical company that discovers, develops, manufactures, and commercializes novel cell therapies for oncology and other indications in the United States, China, and Europe.

Beijing Luzhu Biotechnology

Market Cap: HK$4.3b

A biotechnology company, focuses on the research and development, production, and sale of human vaccines and therapeutic biologics to prevent and control infectious diseases, and treat cancer and autoimmune diseases in Mainland China.

Dizal (Jiangsu) Pharmaceutical

Market Cap: CN¥29.4b

A biopharmaceutical company, discovers, develops, and commercializes therapeutics for the treatment of cancer and immunological diseases.

Ascelia Pharma

Market Cap: SEK 363.3m

A biotech company, develops identifies, develops, and commercializes novel drugs to treat orphan oncology treatments in Sweden.

Xspray Pharma

Market Cap: SEK 1.1b

A pharmaceutical company, engages in the development of protein kinase inhibitors for targeted cancer treatments in Sweden.

Valneva

Market Cap: €657.0m

A specialty vaccine company, develops, manufactures, and commercializes prophylactic vaccines for infectious diseases with unmet needs.

Tenaya Therapeutics

Market Cap: US$221.5m

A clinical-stage biotechnology company, discovers, develops, and delivers therapies for heart disease in the United States.

Achieve Life Sciences

Market Cap: US$233.2m

A late-stage pharmaceutical company, develops and commercializes cytisinicline for nicotine independence in Canada, the United States, and the United Kingdom.

Soleno Therapeutics

Market Cap: US$2.7b

A clinical-stage biopharmaceutical company, focuses on the development and commercialization of novel therapeutics for the treatment of rare diseases.

RenovoRx

Market Cap: US$27.5m

A clinical-stage biopharmaceutical company, engages in the developing of targeted combination therapies to enhance therapeutic outcomes for cancer patients undergoing treatment.

Lineage Cell Therapeutics

Market Cap: US$455.6m

A clinical-stage biotechnology company, develops novel cell therapies for neurological and ophthalmic conditions in the United States and internationally.

Aldeyra Therapeutics

Market Cap: US$303.8m

A biotechnology company, discovers and develops therapies designed to treat immune-mediated and metabolic diseases.

ARS Pharmaceuticals

Market Cap: US$811.5m

A biopharmaceutical company, develops and commercializes treatments for severe allergic reactions.

Pelthos Therapeutics

Market Cap: US$103.1m

A bio-pharmaceutical company, develops and commercializes therapeutic products to help patients with unmet treatment burdens.

Capricor Therapeutics

Market Cap: US$256.0m

A clinical-stage biotechnology company, engages in the development of transformative cell and exosome-based therapeutics for treating duchenne muscular dystrophy (DMD) and other diseases with unmet medical needs in the United States.

Immutep

Market Cap: AU$412.1m

A biotechnology company, engages in developing novel Lymphocyte Activation Gene-3 related immunotherapies for cancer and autoimmune diseases in Australia.

Aelis Farma

Market Cap: €14.8m

A clinical-stage biopharmaceutical company, focuses on discovering and developing drug candidates for the treatment of central nervous system disorders in France.

Lipigon Pharmaceuticals

Market Cap: SEK 59.3m

Develops drugs for lipid related diseases in Sweden.

Precigen

Market Cap: US$1.7b

A discovery and clinical-stage biopharmaceutical company, develops gene and cell therapies using precision technology to target diseases in areas of immuno-oncology, autoimmune disorders, and infectious diseases.

Viridian Therapeutics

Market Cap: US$2.7b

Engages in discovering, developing, and commercializing treatments for serious and rare diseases.